Category: News

In Nature Aging, researchers have discovered how growth differentiation factor 3 (GDF3), a cytokine that increases with aging, is related to more inflammatory macrophages in older animals. Fat and inflammation We have recently reported on a potential treatment for visceral fat, as this kind of fat is known to generate health problems, including an increase...

Researchers have investigated the reporting quality of preclinical studies' outcomes in anti-aging research. They analyzed how study quality changed over time, shortcomings in research, and the improvements that can be made in the future in order to yield as many valuable insights as possible [1]. The need for quality Aging research has grown substantially; however,...

Scientists have investigated a little-known mechanism that fuels cellular senescence: mitochondrial RNA leaking into the cytoplasm. Targeting this mechanism showed promise in a mouse model of fatty liver [1]. The new target The increasing abundance of senescent cells with age has been linked to numerous diseases and is considered a hallmark of aging. Understanding why...

In Aging, researchers have described how they removed visceral fat from older male mice by targeting the metabolic regulatory protein CD47. A key regulator of metabolism Visible fat carried around the body is subcutaneous fat. While this kind of fat is obviously not healthy to have in large amounts, it is not as immediately dangerous...

A new observational study spanning two human cohorts has found a link between theobromine, a phytochemical abundant in cocoa, and slower epigenetic aging [1]. A yummy geroprotector? Popular wisdom has it that not many things in life are both healthy and delicious, but according to research, one of them is chocolate. Studies have repeatedly linked...

In Aging Cell, researchers have described how an age-related deficiency in another compound leads the antioxidant FoxO1 to contribute to bone deterioration in osteoporosis by siphoning from a bone-building pathway. A harmful antioxidant? Because they fight against harmful reactive oxygen species (ROS), antioxidants, both external and internal, are normally viewed as having positive effects against...